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Carbonic Anhydrase III

概要

Name:Carbonic anhydrase III
Target Synonym:Carbonic Anhydrase III, Muscle Specific,Carbonic Anhydrase 3,Epididymis Secretory Sperm Binding Protein Li 167mP,Carbonic Anhydrase IIII,Carbonic anhydrase III,EC:4.2.1.1,Carbonate Dehydratase III,CA3,HEL-S-167mP,CA-III,EC 4.2.1.1,Car3,CAIII
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Approved

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Synonym Name

CA3,Carbonic anhydrase 3

Background

Carbonic anhydrase 3 (CA3) is also known as Carbonate dehydratase III, Carbonic anhydrase III, which belongs to the alpha-carbonic anhydrase family. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The catalytic activity of carbonic anhydrase 3 is activated by proton donors such as imidazole and the dipeptide histidylhistidine and is inhibited by coumarins and sulfonamide derivatives such as acetazolamide.

Clinical and Translational Updates

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